cumulus oophorus การใช้

• The chemotactic gradients of progesterone have been confirmed as the signal emanating from the cumulus oophorus cells surrounding rabbit and human oocytes.
• This results in an expanding or dispersed pattern of the cumulus oophorus around the egg cell, facilitating its identification within follicular fluid . This leads to improved maturation and quality of the oocytes.
• However, in mid-2006 the FDA cleared a device that allows embryologists to select mature sperm for ICSI based on sperm binding to hyaluronan, the main constituent of the gel layer ( cumulus oophorus ) surrounding the oocyte.
• By command of an oocyte-secreted morphogenic gradient, the antral follicle's granulosa cells begin to differentiate themselves into four distinct subtypes : " corona radiata " that surrounds the zona pellucida, " membrana " that's interior to the basal lamina, " periantral " that's adjacent to the antrum, and " cumulus oophorus " that connects the membrana and corona radiata granulosa cells together.